Quality of life in patients with recurrent aphthous stomatitis treated with a mucoadhesive patch containing citrus essential oil
Authors K├╝rkl├╝-G├╝rleyen E, ├ľ─č├╝t-Eri┼čen M, ├çak─▒r O, Uysal ├ľ, Ak G
Received 16 February 2016
Accepted for publication 5 April 2016
Published 27 May 2016 Volume 2016:10 Pages 967—973
Checked for plagiarism Yes
Review by Single-blind
Peer reviewers approved by Dr Lucy Goodman
Peer reviewer comments 4
Editor who approved publication: Dr Johnny Chen
Esma Kürklü-Gürleyen,1 Merve Ö─čüt-Eri┼čen,1 Onur Çak─▒r,1 Ömer Uysal,2 Gülsüm Ak1
1Department of Oral Surgery, Faculty of Dentistry, Istanbul University, 2Department of Biostatistics and Medical Informatics, Faculty of Medicine, BezmiÂlem Vakif University, Istanbul, Turkey
Purpose: To assess 1) patient satisfaction of a mucoadhesive biopatch with citrus essential oil and 2) the change in pain severity and the oral health-related quality of life in patients with recurrent aphthous stomatitis.
Patients and methods: Thirty-seven patients with recurrent aphthous stomatitis participated in the study. Baseline records of personal data, ulcer assessment, visual analog scale, and Oral Health Impact Profile-14 were documented. A mucoadhesive patch was applied over the ulcer. Patients were recommended more applications if pain continued. On the fifth day, a post-therapy assessment was made.
Results: The mean visual analog scale scores at baseline and posttreatment were significantly different (7.3±2.11 and 4.9±2.6, respectively; P=0.001). The mean duration of pain reduced after patch application. The mean total Oral Health Impact Profile-14 scores before and after treatment showed a statistically significant difference (P=0.001). In total, 78.4% of patients reported a considerable improvement in oral functions after treatment (P=0.008).
Conclusion: The mucoadhesive biopatch containing citrus essential oil resulted in satisfying pain alleviation and restoration of oral functions with a significant improvement in the oral health-related quality of life.
Keywords: recurrent aphthous stomatitis, pain, quality of life, essential oil, biopatch, local therapy
This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License. By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.Download Article [PDF] View Full Text [HTML][Machine readable]