Dr Adam D Bachstetter

Dr Adam D Bachstetter

Department of Neuroscience, University of Kentucky, Lexington, KY, USA

Dr. Adam Bachstetter is an Associate Professor of Neuroscience at the University of Kentucky. His primary affiliation is with the Spinal Cord and Brain Research center at the University of Kentucky. He is also affiliated with the Sanders-Brown Center on Aging at the University of Kentucky.

Dr. Bachstetter completed his Ph.D. from the University of South Florida, where he described the function of the CX3CR1/CX3CL1, microglia/neuron communication, in age-related decreases in neuroplasticity and neurogenesis. He then completed a postdoctoral fellowship at Northwestern University on CNS drug discovery, where he contributed to the development of two brain-specific small molecule compounds designed to modify neuroinflammation. Following this he completed postdoctoral training at the University of Kentucky on signal transduction mechanisms regulating neuroinflammation. Dr. Bachstetter described the essential role of p38 MAPK in microglia-mediated neuroinflammation. He completed additional postdoctoral training in human neuropathology at the University of Kentucky, where he described the role of dystrophic microglia in Alzheimer's disease and related dementias.

Research in Dr. Bachstetter's laboratory is focused on therapeutic approaches to target neuroinflammation following traumatic brain injury or in Alzheimer's disease and related dementias. His research also focuses on the cellular process involved in microglia and astrocyte degeneration in neurodegenerative diseases and how the degeneration of the glia alters homeostatic neuron-glia interactions.

Updated 19 September 2023