Back to Journals » Clinical Ophthalmology » Volume 9

Prospective, noncomparative, nonrandomized case study of short-term outcomes of 360° suture trabeculotomy ab interno in patients with open-angle glaucoma

Authors Sato T, Hirata A, Mizoguchi T

Received 13 October 2014

Accepted for publication 26 November 2014

Published 5 January 2015 Volume 2015:9 Pages 63—68

DOI https://doi.org/10.2147/OPTH.S75739

Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 4

Editor who approved publication: Dr Scott Fraser

Video abstract presented by Tomoki Sato

Views: 2199

Tomoki Sato,1 Akira Hirata,2 Takanori Mizoguchi3

1Sato Eye Clinic, Arao City, Kumamoto, 2Hayashi Eye Hospital, Fukuoka, 3Mizoguchi Eye Clinic, Nagasaki, Japan

Background: In this paper, we describe 360° suture trabeculotomy (360°LOT) ab interno and the short-term course in patients who underwent this procedure.
Methods: We prospectively studied 12 patients (12 eyes) with open-angle glaucoma who underwent 360°LOT ab interno at the Sato Eye Clinic between February and July 2014. The surgical procedure involved making a 1.7 mm temporal corneal incision, exposing an approximately 15° opening in the inner wall of Schlemm’s canal (nasal side) using a Trabectome with a gonioscope, and inserting a 5-0 nylon suture rounded at the tip into Schlemm’s canal opened via the anterior chamber. The suture was then threaded around Schlemm’s canal, and the tip of the suture that emerged on the other side was then advanced through the opening to make a circumferential incision. Intraocular pressure (IOP), number of anti-glaucoma medications used, complications, and the surgery completion rate were prospectively studied.
Results: Mean IOP, which was 19.4 mmHg at baseline, showed a significant decrease at each of the monthly observation points, reaching 13.8 mmHg at 6 months after surgery (P=0.0004, paired t-test). The mean number of anti-glaucoma medications decreased from 3.2 at baseline to 1.1 at 6 months after surgery. IOP spikes ≥30 mmHg were seen in 25% of patients, but there were no other serious complications and the surgery completion rate was 92%.
Conclusion: The 360°LOT ab interno procedure preserves the conjunctiva and sclera, and has a high surgery completion rate when using the anterior chamber approach, and could therefore be an effective short-term treatment of open-angle glaucoma.

Keywords: non-penetrating surgery, intraocular pressure, Schlemm’s canal, corneal incision, Trabectome

Creative Commons License This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License. By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.

Download Article [PDF]  View Full Text [HTML][Machine readable]

 

Other article by this author:

Readers of this article also read:

Evaluation of lid speculum with a drape (LiDrape®) for preventing surgical-field contamination

Urano T, Kasaoka M, Sagawa K, Yamakawa R

Clinical Ophthalmology 2015, 9:1227-1232

Published Date: 8 July 2015

Topical difluprednate for the treatment of Harada’s disease

Onishi SM, Asahi MG, Chou C, Gallemore RP

Clinical Ophthalmology 2015, 9:157-167

Published Date: 21 January 2015

Optic neuropathy associated with the use of over-the-counter sexual enhancement supplements

Karli SZ, Liao SD, Carey AR, Lam BL, Wester ST

Clinical Ophthalmology 2014, 8:2171-2175

Published Date: 29 October 2014

Survey of Japanese ophthalmic surgeons regarding perioperative disinfection and antibiotic prophylaxis in cataract surgery

Matsuura K, Mori T, Miyamoto T, Suto C, Saeki Y, Tanaka S, Kawamura H, Ohkubo S, Tanito M, Inoue Y

Clinical Ophthalmology 2014, 8:2013-2018

Published Date: 29 September 2014

Intracameral phenylephrine and ketorolac injection (OMS302) for maintenance of intraoperative pupil diameter and reduction of postoperative pain in intraocular lens replacement with phacoemulsification

Lindstrom RL, Loden JC, Walters TR, Dunn SH, Whitaker JS, Kim T, Demopulos GA, Tjia K

Clinical Ophthalmology 2014, 8:1735-1744

Published Date: 5 September 2014

Characterization of micro-invasive trabecular bypass stents by ex vivo perfusion and computational flow modeling

Hunter KS, Fjield T, Heitzmann H, Shandas R, Kahook MY

Clinical Ophthalmology 2014, 8:499-506

Published Date: 11 March 2014

Congenital agenesis of internal carotid artery with ipsilateral Horner presenting as focal neurological symptoms

Wassim Farhat, Rechdi Ahdab, Hassan Hosseini

Vascular Health and Risk Management 2011, 7:37-40

Published Date: 26 January 2011

PowerPoint or chalk and talk: Perceptions of medical students versus dental students in a medical college in India

Vikas Seth, Prerna Upadhyaya, Mushtaq Ahmad, et al.

Advances in Medical Education and Practice 2010, 1:11-16

Published Date: 30 August 2010