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Primary Pure Squamous Cell Carcinoma of Kidney Associated with Multiple Stag Horn Stones

Authors Hosseinzadeh M, Mohammadzadeh S

Received 8 May 2020

Accepted for publication 25 June 2020

Published 9 July 2020 Volume 2020:13 Pages 261—263


Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 2

Editor who approved publication: Professor Ronald Prineas

Massood Hosseinzadeh, Sahand Mohammadzadeh

Department of Pathology, Shiraz University of Medical Sciences, Shiraz, Iran

Correspondence: Sahand Mohammadzadeh
Department of Pathology, Shiraz University of Medical Sciences, Shiraz, Iran
Tel +989173078147
Fax +9871323017

Abstract: Primary Squamous cell carcinoma (SCC) of the kidney is rarely reported in the literature. It is usually associated with renal stone, and due to lack of clinical symptoms and radiological diagnostic features, patients often present at the late stages of the disease. We reported a 59-year-old woman presented with a longstanding history of flank pain and hematuria. Imaging techniques revealed enlargement of the right kidney associated with multiple staghorn stones. The patient subsequently underwent right radical nephrectomy, and histopathological examination of the mass revealed well-differentiated keratinized squamous cell carcinoma. There was no primary source for her SCC. Although the primary SCC of the kidney is a rare entity, it should be considered in patients with longstanding renal calculi, particularly for large staghorn stones of renal pelvis. On the other hand, conventional imaging could not detect this type of malignancy. In most cases, CT and MRI play an essential role in the diagnosis of such tumors.

Keywords: squamous cell carcinoma, kidney, staghorn stone

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