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Prevalence of refractive errors in children with retinoblastoma

Authors Villegas VM, Wu SC, Murray TG, Cavuoto KM, Capo H, McKeown CA

Received 19 November 2018

Accepted for publication 21 January 2019

Published 25 February 2019 Volume 2019:13 Pages 431—435


Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 3

Editor who approved publication: Dr Scott Fraser

Victor M Villegas,1,2 Shuo-Chieh Wu,1 Timothy G Murray,2 Kara M Cavuoto,1 Hilda Capo,1 Craig A McKeown1

1Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, FL, USA; 2Miami Ocular Oncology and Retina, Miami, FL, USA

Purpose: The main purpose of this study was to investigate refractive errors in children with unilateral and bilateral retinoblastoma (RB).
Methods: An institutional review board–approved consecutive retrospective cohort study was undertaken. Subjects underwent examination under general anesthesia as part of their RB follow-up, which included evaluation by a single pediatric ophthalmologist. Cycloplegic retinoscopy was performed and keratometry data assessed with a handheld Retinomax K Plus 3 keratorefractometer (Righton Ophthalmic Instruments).
Results: The study included 61 eyes of 37 subjects, with 18 (49%) males and 19 females. Seventeen eyes (28%) had hyperopia with spherical equivalent ≥3 D. Refractive astigmatism ≥1.5 D was present in 32% of all eyes. Nine (38%) subjects had anisometropia ≥2 D. Fifteen (63%) subjects had anisometropia ≥1 D.
Conclusion: This study reports the high proportion of amblyogenic refractive risk factors in children with RB, both in RB-affected eyes and contralateral normal eyes.

Keywords: retinoblastoma, hyperopia, myopia, astigmatism, amblyopia, anisometropia

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