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Prevalence of dyslipidemia and prediction of 10-year CVD risk among older adults living in southeast coastal regions in China: a cross-sectional study

Authors Lin HQ, Wu JY, Chen ML, Chen FQ, Liao YJ, Wu YT, Guo ZJ

Received 5 March 2019

Accepted for publication 1 May 2019

Published 20 June 2019 Volume 2019:14 Pages 1119—1129

DOI https://doi.org/10.2147/CIA.S207665

Checked for plagiarism Yes

Review by Single-blind

Peer reviewers approved by Dr Bik-Wai Bilvick Tai

Peer reviewer comments 2

Editor who approved publication: Dr Zhi-Ying Wu


Hui-Qin Lin,1* Jing-Ying Wu,2* Mei-Li Chen,3 Feng-Qiang Chen,4 Yan-Jun Liao,5 Yu-Ting Wu,1 Zhi-Jun Guo1

1Departments of Geriatric, The First Hospital of Quanzhou Affiliated to Fujian Medical University, Quanzhou, People’s Republic of China; 2Department of Cardiology, The Second Hospital Affiliated to Fujian Medical University, Quanzhou, People’s Republic of China; 3Physical Examination Center, Medical College of Quanzhou, Quanzhou, People’s Republic of China; 4Luoshan Community Health Center of Jinjiang, Quanzhou, People’s Republic of China; 5Departments of Intensive Care Unit, The First Hospital of Quanzhou Affiliated to Fujian Medical University, Quanzhou, People’s Republic of China

*These authors contributed equally to this work

Objective: This study aims to analyze the prevalence of dyslipidemia and identify the cardiovascular disease (CVD) risk stratification among older adults living in Quanzhou, China’s southeast coastal region, where the ancient Maritime Silk Road starts.
Methods: A population-based cross-sectional survey of 2,018 adults was conducted in 60–98-year-old residents in Quanzhou from September 2016 to March 2018 using multistage stratified cluster random sampling. The 10-year CVD risk was also estimated by applying the Chinese model recommended by the Chinese Guidelines for Prevention of Cardiovascular Diseases.
Results: The overall prevalence of dyslipidemia among older adults was 56.8%. The prevalence of high total cholesterol (TC), high low-density lipoprotein cholesterol (LDL-C), low high-density lipoprotein cholesterol (HDL-C) and high triglyceride (TG) were 8.4%, 13.9%, 23.1% and 11.4%, respectively. The mean levels of TC, LDL-C, HDL-C and TG were 5.12±1.18, 3.37±0.81, 1.03±0.27 and 1.65±0.76 mmol/L, respectively. Older adults had low risk, moderate risk and high risk for CVD, which were 49.7%, 36.8% and 13.5%, respectively. Age, body mass index and abdominal obesity were significantly associated with the risk of increasing LDL-C levels and were positively correlated to CVD risk.
Conclusion: The prevalence of high TC, high LDL-C, low HDL-C and high TG was relatively low among older adults in Quanzhou, but their lipid levels were high. Approximately half of the elderly adults had moderate or high CVD risk. The personalized primary prevention and control of CVD are recommended for elderly people to identify high-risk individuals.

Keywords: prevalence, prediction, dyslipidemia, CVD risk, older adults

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