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Practical guidance for the use of cyclosporine ophthalmic solutions in the management of dry eye disease

Authors de Oliveira RC, Wilson SE

Received 12 March 2019

Accepted for publication 7 June 2019

Published 1 July 2019 Volume 2019:13 Pages 1115—1122

DOI https://doi.org/10.2147/OPTH.S184412

Checked for plagiarism Yes

Review by Single-blind

Peer reviewers approved by Dr Colin Mak

Peer reviewer comments 2

Editor who approved publication: Dr Scott Fraser


Rodrigo Carlos de Oliveira, Steven E Wilson

Cole Eye Institute, Cleveland Clinic, Cleveland, OH, USA

Abstract: Dry eye disease (DED) is a multifactorial disease of ocular surface and tear film, and is a common disorder treated by eye care providers. It is well established that ocular surface inflammation has an important role in the pathophysiology of DED and that anti-inflammatory cyclosporine A (CsA) improves the treatment outcomes of most patients with DED. The purpose of this review is to provide guidance for practitioners in the use of topical CsA for the management of DED to improve patient satisfaction and the quality of life.

Keywords: keratoconjunctivitis sicca, dry eye disease, cyclosporine A


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