Back to Journals » International Journal of Nanomedicine » Volume 10 » Issue 1

Potential toxicity of dental nanomaterials to the central nervous system

Authors Solla D, Paiva T, André M, Paiva W

Received 6 July 2015

Accepted for publication 8 July 2015

Published 3 September 2015 Volume 2015:10(1) Pages 5593—5596

DOI https://doi.org/10.2147/IJN.S91856

Checked for plagiarism Yes

Editor who approved publication: Dr Thomas J Webster


Davi Fontoura Solla,1 Tatiana Saito Paiva,2 Marcia André,2 Wellingson Silva Paiva1,3

1Department of Neurology, University of Sao Paulo Medical School, 2Department of Surgery, Prosthesis, and Maxillofacial Traumatology, University of Sao Paulo Dentistry School, 3Neurology Center, Samaritano Hospital, Sao Paulo, Brazil

It was enlightening to read this comprehensive review of dental nanomaterials toxicity to the central nervous systems (CNSs) by Feng et al1 published in the International Journal of Nanomedicine. There are many potential applications of nanomaterials in
dentistry.2 Composite resins have been widely used in restorations of dental caries;3 however, it is estimated that approximately 50% of prepared restorations need to be remade, the secondary caries is one of the most frequent causes of failure,4 and the use of nanomaterials could decrease the incidence of these complications. Thus, the application of nanomaterials can bring numerous benefits in dentistry, especially in caries prevention; however, there is an important question about the safety of these materials for the nervous system. In the study by Feng et al1 a vast array of nanomaterials types and their major applications were outlined.

View original article by Feng and colleagues.


Creative Commons License This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License. By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.

Download Article [PDF]  View Full Text [HTML][Machine readable]