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Posterior corneal curvature changes following Refractive Small Incision Lenticule Extraction

Authors Ganesh S, Patel U, Brar S

Received 10 March 2015

Accepted for publication 19 May 2015

Published 21 July 2015 Volume 2015:9 Pages 1359—1364

DOI https://doi.org/10.2147/OPTH.S84354

Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 3

Editor who approved publication: Dr Scott Fraser


Sri Ganesh, Utsav Patel, Sheetal Brar

Phaco and Refractive Surgery Department, Nethradhama Superspeciality Eye Hospital, Bengaluru, Karnataka, India

Purpose: To compare the posterior corneal curvature changes, in terms of corneal power and asphercity, following Refractive Small Incision Lenticule Extraction (ReLEx SMILE) procedure for low, moderate, and high myopia.
Methods: This retrospective, non randomized, comparative, interventional trial; included 52 eyes of 26 patients, divided in three groups: low myopia (myopia ≤3 D [diopters] spherical equivalent [SE]), moderate myopia (myopia >3 D and <6 D SE), and high myopia (myopia ≥6 D SE). All patients were treated for myopia and myopic astigmatism using ReLEx SMILE. The eyes were examined pre-operatively and 3 months post-operatively using SCHWIND SIRIUS, a three-dimensional rotating Scheimpflug camera with a Placido disc topographer to assess corneal changes with regard to keratometric power and asphericity of the cornea.
Results: A statistically significant increase in mean keratometric power in the 3, 5, and 7 mm zones of the posterior corneal surface compared with its pre-ReLEx SMILE value was detected after 3 months in the moderate myopia group (pre-operative [pre-op] -6.14±0.23, post-operative [post-op] -6.29±0.22, P<0.001) and high myopia group (pre-op -6.19±0.16, post-op -6.4±0.18, P<0.001), but there was no significant change in keratometric power of the posterior surface in the low myopia group (pre-op -5.87±0.17, post-op -6.06±0.29, P=0.143). Asphericity (Q-value) of the posterior surface changed significantly (P<0.001) after ReLEx SMILE in the moderate myopia group in the 3, 5, and 7 mm zones, and in the high myopia group in the 3 and 7 mm zones; but there was no significant change in the Q-value in the low myopia group in all three zones (pre-op 0.23±0.43, post-op -0.40±0.71, P=0.170), and in the high myopia group in the 5 mm zone (P=0.228).
Conclusion: ReLEx SMILE causes significant changes in posterior corneal keratometric power and asphericity in moderate and high myopia, but the effect is subtle and insignificant in low myopia.

Keywords: ReLEx SMILE, Refractive Small Incision Lenticule Extraction, posterior curvature, corneal keratometric power, corneal asphericity

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