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PCORnet’s Collaborative Research Groups

Authors Pletcher MJ, Forrest CB , Carton TW

Received 9 October 2017

Accepted for publication 8 December 2017

Published 9 February 2018 Volume 2018:9 Pages 91—95


Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 2

Editor who approved publication: Dr Liana Bruce

Mark J Pletcher,1,2 Christopher B Forrest,3 Thomas W Carton4

1Department of Epidemiology and Biostatistics, University of California, San Francisco, CA, 2Division of General Internal Medicine, Department of Medicine, University of California, San Francisco, CA, 3Applied Clinical Research Center, Children’s Hospital of Philadelphia, Philadelphia, PA, 4Division of Health Services Research, Louisiana Public Health Institute, New Orleans, LA, USA

Abstract: The Patient-Centered Outcomes Research Institute (PCORI) launched a multi-institutional “network of networks” in 2013 – Patient-Centered Clinical Research Network (PCORnet) – that is designed to conduct clinical research that is faster, less expensive, and more responsive to the information needs of patients and clinicians. To enhance cross-network and cross-institutional collaboration and catalyze the use of PCORnet, PCORI has supported formation of 11 Collaborative Research Groups focusing on specific disease types (e.g., ­cardiovascular health and cancer) or particular patient populations (e.g., pediatrics and health disparities). PCORnet’s Collaborative Research Groups are establishing research priorities within these focus areas, establishing relationships with potential funders, and supporting development of specific research projects that will use PCORnet resources. PCORnet remains a complex, multilevel, and heterogeneous network that is still maturing and building a diverse portfolio of observational and interventional people-centered research; engaging with PCORnet can be daunting, particularly for outside investigators. We believe the Collaborative Research Groups are stimulating interest and helping investigators navigate the complexity, but only time will tell if these efforts will bear fruit in terms of funded multicenter PCORnet projects.

Keywords: PCORI, PCORnet, network, collaboration, infrastructure


The authors would like to thank Jennifer Paulakovich from the PCORnet Coordinating Center, Kim Marschhauser from the Patient-Centered Outcomes Research Institute, and Collaborative Research Group staff and leadership who helped gather and verify information presented herein about the CRG Program. The writing of this article was funded in part through contracts from the Patient-Centered Outcomes Research Institute, including PPRN-1306-04709, CDRN-1306-01556, and CDRN-1306-04864.


The authors report no conflicts of interest in this work besides the funding they receive from PCORI for the Collaborative Research Group program.



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