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Back to Journals » Journal of Pain Research » Volume 9
Pain in the management of opioid use disorder
Received 1 October 2016
Accepted for publication 10 October 2016
Published 4 November 2016 Volume 2016:9 Pages 963—966
DOI https://doi.org/10.2147/JPR.S123667
Checked for plagiarism Yes
Editor who approved publication: Dr Michael Schatman
Sunil Sirohi,1 Amit K Tiwari2
1Laboratory of Endocrine and Neuropsychiatric Disorders, Division of Basic Pharmaceutical Sciences, College of Pharmacy, Xavier University of Louisiana, New Orleans, LA, 2Department of Pharmacology and Experimental Therapeutics, College of Pharmacy and Pharmaceutical Sciences, University of Toledo, Toledo, OH, USA
Opioids remain the drug of choice for the clinical management of moderate to severe pain. However, in addition to their most effective analgesic actions, opioids also produce a sense of well-being and euphoria, which may trigger significant concerns associated with their use.1 In fact, there has been an alarming increase in prescription opioid use, abuse and illicit use; and according to the National Center for Health Statistics, the total number of deaths related to opioid overdose has more than tripled from 2011 to 2014.2–5 Although representing 5.0 % of the global population, studies report that Americans consume 80% of the global opioid supply,3 and the United States is experiencing an opioid abuse epidemic.6 Considering this unprecedented rise in opioid consumption, the United States Centers for Disease Control and Prevention has listed prescription opioid overdose among one of the 10 most important public health problems in all the 50 states.7
Acknowledgments
This publication was made possible with partial funding from the NIMHD-RCMI grant number 5G12MD007595 from the National Institute on Minority Health and Health Disparities and the NIGMS-BUILD grant number 8UL1GM118967 to SS. This publication was also made possible by the Louisiana Cancer Research Consortium. University of Toledo provided start-up funds (F-110760) to AKT. We thank Ms. Charisse Montgomery (UT), Dr. Thomas J Maestri (XULA) and Ms. Anna Smith (XULA) for the critical review of this manuscript. The contents are solely the responsibility of the authors and do not necessarily represent the official views of NIMHD.
Disclosure
The authors report no conflicts of interest in this work.
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