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Optic nerve sheath meningiomas: prevalence, impact, and management strategies

Authors Parker RT, Ovens CA, Fraser CL, Samarawickrama C

Received 10 April 2018

Accepted for publication 10 July 2018

Published 24 October 2018 Volume 2018:10 Pages 85—99


Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 3

Editor who approved publication: Professor Margaret Wong-Riley

Video abstract presented by Richard Parker.

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Richard T Parker,1 Christopher A Ovens,1 Clare L Fraser,2 Chameen Samarawickrama1,3

1Sydney Medical School, Discipline of Clinical Ophthalmology and Eye Health, University of Sydney, Sydney, NSW, Australia; 2Save Sight Institute, University of Sydney, Sydney, NSW, Australia; 3Department of Ophthalmology, Faculty of Medicine, South Western Sydney Clinical School, University of New South Wales, Sydney, NSW, Australia

Abstract: Optic nerve sheath meningiomas are rare benign neoplasms of the meninges surrounding the optic nerve. They are a significant cause of morbidity. While the mortality rate is practically zero, these tumors can blind or disfigure patients. Given that the clinical course can be variable, and treatment has the capacity to cause morbidity itself, the management of these patients can be difficult. We review the literature to discuss the prevalence of optic nerve sheath meningiomas, the association with neurofibromatosis type 2, natural history, and management options and strategies.

Keywords: meningioma, optic nerve neoplasms, neurofibromatosis 2, radiotherapy, imaging

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