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Novel drug-eluting stents in the treatment of de novo coronary lesions

Authors Capodanno D, Dipasqua F, Tamburino C

Published 25 February 2011 Volume 2011:7 Pages 103—118

DOI https://doi.org/10.2147/VHRM.S11444

Review by Single-blind

Peer reviewer comments 3


Davide Capodanno1,2, Fabio Dipasqua1, Corrado Tamburino1,2
1Department of Cardiology, Ferrarotto Hospital, University of Catania, Catania, Italy; 2ETNA Foundation, Catania, Italy

Abstract: Due to safety concerns in recent years, much effort has been devoted to improving the outcomes associated with drug-eluting stents (DESs). This review summarizes the current status of methodological and technical achievements reported in second-generation DES. Novel stents are described based on the component (the platform, the polymer, and the drug) that has undergone the most significant changes compared to earlier generation DES. An overview of the currently available evidence on the use of novel coronary devices in patients undergoing coronary revascularization is also reviewed.

Keywords: coronary artery disease, stent, platform, polymer, drug, percutaneous coronary intervention, late lumen loss, follow-up, outcomes

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