New corneal assessment index from the relational thickness and other OCULUS values (CAIRO Index)
Received 20 April 2018
Accepted for publication 13 June 2018
Published 23 August 2018 Volume 2018:12 Pages 1527—1532
Checked for plagiarism Yes
Review by Single-blind
Peer reviewer comments 3
Editor who approved publication: Dr Scott Fraser
Maged M Roshdy,1,2 Sherine S Wahba,1,2 Ramy R Fikry2,3
1Ophthalmology Department, Ain Shams University, Cairo, Egypt; 2Ophthalmology Department, Al Watany Eye Hospital, Cairo, Egypt; 3Ophthalmology Department, Cairo University, Cairo, Egypt
Purpose: The aim of this study was to find indices for keratoconus (KC) detection with higher sensitivity and specificity than the currently available ones with the rotating Scheimpflug imaging (Oculyzer I, Pentacam) software.
Patients and methods: Data of 103 normal and 73 KC eyes imaged by Oculyzer I, including slit-lamp examination, refraction, Scheimpflug images, and follow-up data were collected. Logistic regression was done to find new indices with higher area under receiver operating characteristic curves using the currently available ones.
Results: The Corneal Assessment Index from Relational thickness and other OCULUS Values 9 (CAIRO 9) index, deduced from the Ambrosio relational thickness-maximum and the anterior elevation at thinnest point from 9 mm best-fit sphere, and the CAIRO 8, deduced from Ambrosio relational thickness-maximum and anterior elevation at thinnest point from 8 mm best-fit sphere, have a very high area under receiver operating characteristic curves for KC detection (0.997 and 0.995, respectively).
Conclusion: New corneal assessment index is deduced with better sensitivity and specificity for KC detection.
Keywords: keratoconus, pentacam, keratoconus indices, elevation, pachymetry, keratoconus diagnosis
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