Neutrophil/lymphocyte ratio and mean platelet volume in central serous chorioretinopathy
Authors Erol MK, Balkarli A, Yucel O, Akar Y, Dogan B, Suren E
Received 1 April 2017
Accepted for publication 11 May 2017
Published 28 July 2017 Volume 2017:13 Pages 945—950
Checked for plagiarism Yes
Review by Single anonymous peer review
Peer reviewer comments 2
Editor who approved publication: Professor Garry Walsh
Muhammet Kazim Erol,1 Ayse Balkarli,2 Ozgur Yucel,1 Yusuf Akar,3 Berna Dogan,1 Elcin Suren1
1Department of Ophthalmology, 2Department of Internal Medicine, Division of Rheumatology, Antalya Education and Research Hospital, 3Department of Ophthalmology, Akdeniz University Medical Faculty, Antalya, Turkey
Purpose: This study aimed to evaluate mean platelet volume (MPV) and neutrophil/lymphocyte ratio (NLR) values and their relationship with clinical findings in patients with central serous chorioretinopathy (CSCR).
Methods: Overall, 87 patients fulfilling inclusion criteria and 320 age- and sex-matched healthy individuals as controls were included in the study. The CSCR patients (n=87) were classified into 2 groups as acute CSCR (group 1, n=43) and chronic CSCR (group 2, n=44).
Results: It was found that NLR (P<0.05) and C-reactive protein (CRP) (P<0.05) values were higher in acute CSCR group than the other groups. MPV value was found to be higher in chronic CSCR group than the other groups (P<0.001).
Conclusion: It seems that neutrophils play a major role in acute CSCR while platelets are involved in progression to chronic CSCR. Larger, prospective studies are needed on this topic.
Keywords: central serous chorioretinopathy, mean platelet volume, neutrophil/lymphocyte ratio
This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License. By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.Download Article [PDF] View Full Text [HTML][Machine readable]