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National antimicrobial stewardship and fluoroquinolone-resistant Clostridium difficile in China

Authors Xiao M, Cheng JW, Kudinha T, Kong F, Xu YC

Received 16 August 2017

Accepted for publication 22 September 2017

Published 13 October 2017 Volume 2017:10 Pages 329—331


Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 2

Editor who approved publication: Dr Joachim Wink

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Meng Xiao,1,* Jing-Wei Cheng,1,2,* Timothy Kudinha,3 Fanrong Kong,4 Ying-Chun Xu1,2

1Department of Clinical Laboratory, Peking Union Medical College Hospital, 2Faculty of Clinical Laboratory Diagnostics, Graduate School, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, China; 3School of Biomedical Sciences, The Charles Sturt University, Leeds Parade, Orange, 4Centre for Infectious Diseases and Microbiology Laboratory Services, ICPMR–Pathology West, Westmead Hospital, University of Sydney, Westmead, NSW, Australia

*These authors contributed equally to this work

In a recent report, Dingle et al showed that national intervention programs aimed at judicious antimicrobial usage, especially restrictions to fluoroquinolones, contributed to a significant decrease in Clostridium difficile infection (CDI) in England.1 This is considered an outstanding achievement in combating antimicrobial resistance worldwide.


This work was supported by a Natural Science Foundation of China (81501807), a Beijing Out-standing Talents Cultivation Program (2015000020124G071), and a PUMCH Youth Research Fund (grant number IH11583).

Author contributions

All authors contributed toward data analysis, drafting and critically revising the paper and agree to be accountable for all aspects of the work.


The authors report no conflicts of interest in this work.



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