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Multiple Chorangioma Following Long-Term Secondary Infertility: A Rare Case Report and Review of Pathologic Differential Diagnosis

Authors Akbarzadeh-Jahromi M, Soleimani N, Mohammadzadeh S

Received 27 August 2019

Accepted for publication 12 December 2019

Published 19 December 2019 Volume 2019:12 Pages 383—387

DOI https://doi.org/10.2147/IMCRJ.S227947

Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 2

Editor who approved publication: Professor Ronald Prineas


Mojgan Akbarzadeh-Jahromi, Neda Soleimani, Sahand Mohammadzadeh

Department of Pathology, Shiraz University of Medical Sciences, Shiraz, Iran

Correspondence: Neda Soleimani
Department of Pathology, Shiraz University of Medical Sciences, Shiraz, Iran
Tel +98 9173422519
Fax +987132301784
Email neda_soleimani61@yahoo.com

Abstract: Chorangioma (placental hemangioma) is a benign non-trophoblastic neoplasm of the placenta. Small chorangiomas are usually asymptomatic, but the giant and multiple ones rarely have a favorable outcome. We report a case of 29 weeks of gestational age (after long-term secondary infertility) with premature labor pain and undiagnosed multiple chorangioma leading to hydrops fetalis and neonatal death. Here we report the clinicopathological features of our case and chorangioma in general, along with comparison of different vascular lesions of placenta in terms of incidence, risk factors, complications, histologic origin, macroscopic and light and electron microscopic features.

Keywords: chorangioma, chorangiomatosis, chorangiosis

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