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Multiplanar Computed Tomographic Analysis of Frontal Cells According to International Frontal Sinus Anatomy Classification and Their Relation to Frontal Sinusitis

Authors Pham HK, Tran TT, Nguyen TV, Thai TT

Received 11 November 2020

Accepted for publication 15 January 2021

Published 4 February 2021 Volume 2021:14 Pages 1—7


Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 4

Editor who approved publication: Professor Tarik Massoud

Huu Kien Pham,1,2 Tai Thanh Tran,2 Thanh Van Nguyen,2 Truc Thanh Thai3

1Department of Otolaryngology, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam; 2Department of Otolaryngology – Head and Neck Surgery, University Medical Center, Ho Chi Minh City, Vietnam; 3Department of Medical Statistics and Informatics, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam

Correspondence: Truc Thanh Thai
Department of Medical Statistics and Informatics, University of Medicine and Pharmacy at Ho Chi Minh City, 217 Hong Bang Street, District 5, Ho Chi Minh City, Vietnam
Tel +84 908 381 266

Background: This study explored the prevalence of frontal cells and the relationship between different types of frontal cells classified using the International Frontal Sinus Anatomy Classification (IFAC) and frontal sinusitis.
Methods: A retrospective cross-sectional study was conducted with 1006 CT scans of paranasal sinuses. Identification of frontal sinus cells was based on IFAC. The scans were classified into no frontal sinusitis, frontal sinusitis, isolated frontal sinusitis, no sinusitis.
Results: Agger nasi cells were the most common (91.9%). The prevalence of supra agger cell (SAC) was 28.7%, while the supra agger frontal cell (SAFC) was only 15.8%, the supra bulla cell (SBC) was 59.7%, the supra bulla frontal cell (SBFC) was 25.8%. Supra orbital ethmoid cell (SOEC) and frontal septal cell (FSC) were identified in 6.9% and 14.3% of the cases, respectively. Patients with SAFCs and SBFCs were significantly more likely to develop frontal sinusitis (Odds Ratio (OR)=1.78, 95% confidence interval (CI) 1.24– 2.56 and OR=2.70, 95% CI 1.98– 3.66). Isolated frontal sinusitis was found in 10 scans and was associated with the presence of SAC (OR=3.76, 95% CI 1.02– 13.90).
Conclusion: In Vietnamese adult patients, frontal cells based on IFAC were prevalent and were associated with frontal sinusitis development, including isolated frontal sinusitis.

Keywords: International Frontal Sinus Anatomy Classification, frontal sinusitis, frontal cells, multiplanar computed tomographic analysis

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