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Multifocal choroiditis following simultaneous hepatitis A, typhoid, and yellow fever vaccination

Authors Escott S, Tarabishy A, Davidorf F

Received 28 August 2012

Accepted for publication 22 September 2012

Published 18 February 2013 Volume 2013:7 Pages 363—365

DOI https://doi.org/10.2147/OPTH.S37443

Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 2


Sarah Escott, Ahmad B Tarabishy, Frederick H Davidorf

Havener Eye Institute, The Ohio State University, Columbus, OH, USA

Abstract: The paper describes the first reported case of multifocal choroiditis following simultaneous hepatitis-A, typhoid, and yellow fever vaccinations. A 33-year-old male developed sudden onset of flashing lights and floaters in his right eye 3 weeks following hepatitis A, typhoid, and yellow fever vaccinations. Fundus examination and angiography confirmed the presence of multiple peripheral chorioretinal lesions. These lesions demonstrated characteristic morphologic changes over a period of 8 weeks which were consistent with a diagnosis of self-resolving multifocal choroiditis. Vaccine-induced intraocular inflammation has been described infrequently. We demonstrate the first case of self-resolving multifocal choroiditis following simultaneous administration of hepatitis A, yellow fever, and typhoid immunizations.

Keywords: multifocal choroiditis, vaccination, hepatitis A, typhoid, yellow fever

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