Back to Journals » Clinical Ophthalmology » Volume 4

Methicillin-resistant Staphylococcus epidermidis isolation from the vitrectomy specimen four hours after initial treatment with vancomycin and ceftazidime

Authors Javey G, Schwartz S, Moshfeghi AA, Asrani S, Flynn Jr. H

Published 25 February 2010 Volume 2010:4 Pages 101—104


Review by Single-blind

Peer reviewer comments 3

Golnaz Javey1, Stephen G Schwartz2, Andrew A Moshfeghi2, Sanjay Asrani3, Harry W Flynn Jr2

1Department of Ophthalmology, Cullen Eye Institute, Baylor College of Medicine, Houston, TX, USA; 2Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA; 3Department of Ophthalmology, Duke University Medical Center, Durham, NC, USA

Abstract: A patient presented with acute-onset, postoperative endophthalmitis and visual acuity of light perception. Because of a time delay in arranging a pars plana vitrectomy (PPV), the patient was treated with a prompt vitreous tap for culture an injection of vancomycin and ceftazidime. Four hours later, the PPV was performed and additional antibiotics were injected. The cultures from both the initial needle tap and the subsequent PPV isolated methicillin-resistant Staphylococcus epidermidis sensitive to vancomycin, but resistant to fourth-generation fluoroquinolones. The patient eventually recovered a visual acuity of 20/80 before developing retinal detachment. This case illustrates the time lag necessary to sterilize the vitreous cavity, and suggests a possible two-step staged treatment strategy for situations in which access to PPV equipment and support staff may be limited.
Keywords: endophthalmitis, pars plana vitrectomy, tap and inject

Creative Commons License This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License. By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.

Download Article [PDF] 


Other articles by this author:

Multimodal images of chronic branch retinal vein occlusion

Schwartz SG, Monroig A, Flynn HW Jr

International Medical Case Reports Journal 2017, 10:159-162

Published Date: 4 May 2017

Update on corticosteroids for diabetic macular edema

Schwartz SG, Scott IU, Stewart MW, Flynn HW Jr

Clinical Ophthalmology 2016, 10:1723-1730

Published Date: 8 September 2016

Genetics and age-related macular degeneration: a practical review for the clinician

Schwartz SG, Hampton BM, Kovach JL, Brantley MA Jr

Clinical Ophthalmology 2016, 10:1229-1235

Published Date: 4 July 2016

Tamponade in the surgical management of retinal detachment

Vaziri K, Schwartz SG, Kishor KS, Flynn HW Jr

Clinical Ophthalmology 2016, 10:471-476

Published Date: 16 March 2016

Antibiotic prophylaxis: different practice patterns within and outside the United States

Schwartz SG, Grzybowski A, Flynn HW Jr

Clinical Ophthalmology 2016, 10:251-256

Published Date: 28 January 2016

Update on genetics and diabetic retinopathy

Hampton BM, Schwartz SG, Brantley MA Jr, Flynn HW Jr

Clinical Ophthalmology 2015, 9:2175-2193

Published Date: 23 November 2015

Pharmacogenetics and nutritional supplementation in age-related macular degeneration

Hampton BM, Kovach JL, Schwartz SG

Clinical Ophthalmology 2015, 9:873-876

Published Date: 15 May 2015

Incidence of postoperative suprachoroidal hemorrhage after glaucoma filtration surgeries in the United States

Vaziri K, Schwartz SG, Kishor KS, Fortun JA, Moshfeghi DM, Moshfeghi AA, Flynn HW Jr

Clinical Ophthalmology 2015, 9:579-584

Published Date: 2 April 2015

Endophthalmitis: state of the art

Vaziri K, Schwartz SG, Kishor K, Flynn HW Jr

Clinical Ophthalmology 2015, 9:95-108

Published Date: 8 January 2015

Pars plana vitrectomy for primary rhegmatogenous retinal detachment

Stephen G Schwartz, Harry W Flynn Jr

Clinical Ophthalmology 2008, 2:57-63

Published Date: 7 March 2008

Readers of this article also read:

Green synthesis of water-soluble nontoxic polymeric nanocomposites containing silver nanoparticles

Prozorova GF, Pozdnyakov AS, Kuznetsova NP, Korzhova SA, Emel’yanov AI, Ermakova TG, Fadeeva TV, Sosedova LM

International Journal of Nanomedicine 2014, 9:1883-1889

Published Date: 16 April 2014

Pharmacokinetics and pharmacodynamics of acetylsalicylic acid after intravenous and oral administration to healthy volunteers

Nagelschmitz J, Blunck M, Kraetzschmar J, Ludwig M, Wensing G, Hohlfeld T

Clinical Pharmacology: Advances and Applications 2014, 6:51-59

Published Date: 19 March 2014

Methacrylic-based nanogels for the pH-sensitive delivery of 5-Fluorouracil in the colon

Ashwanikumar N, Kumar NA, Nair SA, Kumar GS

International Journal of Nanomedicine 2012, 7:5769-5779

Published Date: 15 November 2012

A novel preparation method for silicone oil nanoemulsions and its application for coating hair with silicone

Hu Z, Liao M, Chen Y, Cai Y, Meng L, Liu Y, Lv N, Liu Z, Yuan W

International Journal of Nanomedicine 2012, 7:5719-5724

Published Date: 12 November 2012

Cross-linked acrylic hydrogel for the controlled delivery of hydrophobic drugs in cancer therapy

Deepa G, Thulasidasan AK, Anto RJ, Pillai JJ, Kumar GS

International Journal of Nanomedicine 2012, 7:4077-4088

Published Date: 27 July 2012

Crystallization after intravitreal ganciclovir injection

Pitipol Choopong, Nattaporn Tesavibul, Nattawut Rodanant

Clinical Ophthalmology 2010, 4:709-711

Published Date: 14 July 2010