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Menstrual suppression: current perspectives

Authors Hillard P

Received 31 March 2014

Accepted for publication 16 April 2014

Published 23 June 2014 Volume 2014:6 Pages 631—637

DOI https://doi.org/10.2147/IJWH.S46680

Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 3


Paula Adams Hillard

Department of Obstetrics and Gynecology, Stanford University School of Medicine, Stanford, CA, USA

Abstract: Menstrual suppression to provide relief of menstrual-related symptoms or to manage medical conditions associated with menstrual morbidity or menstrual exacerbation has been used clinically since the development of steroid hormonal therapies. Options range from the extended or continuous use of combined hormonal oral contraceptives, to the use of combined hormonal patches and rings, progestins given in a variety of formulations from intramuscular injection to oral therapies to intrauterine devices, and other agents such as gonadotropin-releasing hormone (GnRH) antagonists. The agents used for menstrual suppression have variable rates of success in inducing amenorrhea, but typically have increasing rates of amenorrhea over time. Therapy may be limited by side effects, most commonly irregular, unscheduled bleeding. These therapies can benefit women's quality of life, and by stabilizing the hormonal milieu, potentially improve the course of underlying medical conditions such as diabetes or a seizure disorder. This review addresses situations in which menstrual suppression may be of benefit, and lists options which have been successful in inducing medical amenorrhea.

Keywords: menstrual molimena, amenorrhea, inducing amenorrhea, quality of life


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