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Management of digital ulcers in systemic sclerosis

Authors Barsotti S, Di Battista M, Venturini V, Della Rossa A, Mosca M

Received 21 February 2019

Accepted for publication 26 April 2019

Published 23 May 2019 Volume 2019:6 Pages 9—18

DOI https://doi.org/10.2147/CWCMR.S181326

Checked for plagiarism Yes

Review by Single-blind

Peer reviewers approved by Dr Colin Mak

Peer reviewer comments 2

Editor who approved publication: Professor Marco Romanelli


Simone Barsotti, Marco Di Battista, Valentina Venturini, Alessandra Della Rossa, Marta Mosca

Rheumatology Unit, Pisa University Hospital, Pisa, Italy

Abstract: Systemic sclerosis (SSc) is a rare disease characterized by autoimmune pathogenesis, alterations to the vascular system, and fibrosis of the skin and internal organs. Digital ulcers (DUs) are common in SSc patients, and represent a major burden for the patients. The management of DUs in systemic sclerosis is difficult, because it needs a multimodal therapeutic approach, as local treatment alone is usually insufficient and also systemic treatment with vasoactive drugs and modification of the lifestyle are usually required for healing of the wounds. In this review, we describe the optimal management of DUs according to recent literature and our clinical practice for systemic and local treatment of chronic digital wounds in SSc patients.

Keywords: systemic sclerosis, wound, digital ulcers, dressings
 

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