Back to Journals » International Journal of Nanomedicine » Volume 3 » Issue 2

Magnetic nanoparticles for gene and drug delivery

Authors McBain SC, Yiu HHP, Dobson J

Published 6 June 2008 Volume 2008:3(2) Pages 169—180

DOI https://doi.org/10.2147/IJN.S1608


Stuart C McBain, Humphrey HP Yiu, Jon Dobson

Institute of Science and Technology in Medicine, Keele University, Thornburrow Drive, Hartshill, Stoke-on-Trent, Staffordshire, ST4 7QB, U.K.

Abstract: Investigations of magnetic micro- and nanoparticles for targeted drug delivery began over 30 years ago. Since that time, major progress has been made in particle design and synthesis techniques, however, very few clinical trials have taken place. Here we review advances in magnetic nanoparticle design, in vitro and animal experiments with magnetic nanoparticle-based drug and gene delivery, and clinical trials of drug targeting.

Keywords: magnetic nanoparticles, gene delivery, biotechnology

Creative Commons License This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License. By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.

Download Article [PDF]