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Long-term surgical outcomes of retinal detachment in patients with Stickler syndrome

Authors Reddy D, Yonekawa Y, Thomas B, Nudleman E, Williams G

Received 27 April 2016

Accepted for publication 8 June 2016

Published 16 August 2016 Volume 2016:10 Pages 1531—1534

DOI https://doi.org/10.2147/OPTH.S111526

Checked for plagiarism Yes

Review by Single-blind

Peer reviewers approved by Dr Amy Norman

Peer reviewer comments 3

Editor who approved publication: Dr Scott Fraser


Devasis N Reddy,1 Yoshihiro Yonekawa,1–4 Benjamin J Thomas,1,2,5 Eric D Nudleman,6 George A Williams1,2

1Oakland University William Beaumont School of Medicine, Rochester, MI, 2Associated Retinal Consultants, William Beaumont Hospital, Royal Oak, MI, 3Massachusetts Eye and Ear Infirmary, Boston, MA, 4Boston Children’s Hospital, Harvard Medical School, Boston, MA, 5Florida Retina Institute, Jacksonville, FL, 6Shiley Eye Institute, University of California San Diego School of Medicine, San Diego, CA, USA

Purpose: The aim of the study was to present the long-term anatomical and visual outcomes of retinal detachment repair in patients with Stickler syndrome.
Patients and methods: This study is a retrospective, interventional, consecutive case series of patients with Stickler syndrome undergoing retinal reattachment surgery from 2009 to 2014 at the Associated Retinal Consultants, William Beaumont Hospital.
Results: Sixteen eyes from 13 patients were identified. Patients underwent a mean of 3.1 surgical interventions (range: 1–13) with a mean postoperative follow-up of 94 months (range: 5–313 months). Twelve eyes (75%) developed proliferative vitreoretinopathy. Retinal reattachment was achieved in 100% of eyes, with ten eyes (63%) requiring silicone oil tamponade at final follow-up. Mean preoperative visual acuity (VA) was 20/914, which improved to 20/796 at final follow-up (P=0.81). There was a significant correlation between presenting and final VA (P<0.001), and patients with poorer presenting VA were more likely to require silicone oil tamponade at final follow-up (P=0.04).
Conclusion: Repair of retinal detachment in patients with Stickler syndrome often requires multiple surgeries, and visual outcomes are variable. Presenting VA is significantly predictive of long-term VA outcomes.

Keywords: pediatric retina, proliferative vitreoretinopathy, retina, scleral buckle, vitrectomy, vitreoretinal surgery

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