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The association between gastric acid inhibitors and delirium in geriatric inpatients: implications for clinical practice and research

Authors Zhu L, Zhou Q

Received 23 April 2016

Accepted for publication 29 April 2016

Published 16 June 2016 Volume 2016:11 Pages 797—799


Checked for plagiarism Yes

Editor who approved publication: Prof. Dr. Zhi-Ying Wu

Ling-ling Zhu,1 Quan Zhou2

1VIP Care Ward, Division of Nursing, the Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang Province, People’s Republic of China; 2Department of Pharmacy, the Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang Province, People’s Republic of China

We read with great interest the prospective observational study by Otremba et al,1 which shows that use of proton-pump inhibitors (PPIs) is one of independent factors associated with development of delirium in geriatric inpatients (odds ratio [OR] =1.67; confidence interval [CI] =1.11–2.53; P=0.014). We especially appreciate their new finding, because PPIs are commonly prescribed in older hospitalized patients. However, we found two points worthy of discussion and we would like to share our perspectives in the following paragraphs.

View original paper by Otremba and colleagues.

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