Lemierre Syndrome. A Forgotten Disease. Case Report and Review of Literature
Authors Pokharel A, Basnet P, Sharma B, Thapa K
Received 10 June 2019
Accepted for publication 16 November 2019
Published 29 November 2019 Volume 2019:12 Pages 367—371
Checked for plagiarism Yes
Review by Single-blind
Peer reviewers approved by Dr Colin Mak
Peer reviewer comments 2
Editor who approved publication: Professor Ronald Prineas
Apar Pokharel,1 Prabhat Basnet,2 Bibek Sharma,1 Kripesh Thapa2
1Department of Otorhinolaryngology and Head and Neck Surgery, College of Medical Sciences, Chitwan, Nepal; 2Department of Radiodiagnosis, College of Medical Sciences, Chitwan, Nepal
Correspondence: Apar Pokharel
Department of Otorhinolaryngology and Head and Neck Surgery, College of Medical Sciences, Chitwan, Nepal
Introduction: Lemierre syndrome is a serious condition that associates oropharyngeal infection and thrombosis of the internal jugular vein (IJV) with subsequent distant septic emboli, most frequently in the lungs.
Case presentation: A 70-year-old female with retropharyngeal abscess developed features of Lemierre syndrome. The condition was managed with serial aspiration of the abscess and prolonged usage of intravenous antibiotics.
Discussion: Lemierre syndrome is most frequently caused by the anaerobic bacterium, Fusobacterium necrophorum. Although rare, there is evidence of a resurgence in the condition in recent years, most probably due to reduced use of antibiotic therapy for sore throats. Although there is a characteristic clinical picture, many clinicians are unaware of this condition, leading to delayed diagnosis with potentially fatal consequences.
Conclusion: Early diagnosis of this condition and prompt treatment with intravenous broad spectrum antibiotics results in a complete resolution of this condition. Surgery is indicated in the case of abscess formation.
Keywords: Lemierre syndrome, Fusobacterium necrophorum, septic thrombophlebitis, retropharyngeal abscess
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