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Lacrimal fossa lesions: a review of 146 cases in Egypt

Authors Eldesouky MA, Elbakary MA, Sabik S, Shareef M

Received 23 March 2014

Accepted for publication 13 May 2014

Published 26 August 2014 Volume 2014:8 Pages 1603—1609

DOI https://doi.org/10.2147/OPTH.S64703

Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 4


Mohammed A Eldesouky,1 Molham A Elbakary,1 Saly Sabik,1 Mohamed M Shareef2

1Oculoplastic Unit, Ophthalmology Department, Faculty of Medicine, Tanta University, 2Pathology Department, Faculty of Medicine, Tanta University, Tanta, Egypt

Purpose: The incidence and clinical and imaging criteria of different pathological forms of lacrimal fossa lesions in the Delta region of Egypt were studied.
Methods: A retrospective study of patients with lacrimal fossa lesions for the past 10 years was conducted. A total of 146 cases were identified. Their medical records were reviewed for clinical and imaging data (computed tomography scan, magnetic resonance imaging scan, or both). A definitive diagnosis based on pathological examination of biopsies was also reviewed.
Results: Among the patients reviewed, 43.15% had inflammatory lacrimal gland lesions, 26.71% had lymphoproliferative lesions, and 21.92% had epithelial lesions; 8.22% had rare lesions (5.48% were dacryops and 2.74% had hemangioma). The study included 71.92% benign lesions and 28.08% malignant lesions, which were distributed between 19.18% malignant lymphoma and 8.9% malignant epithelial tumors. According to the pathological origin of the lesions, they may be classified into 78.08% nonepithelial lesions and 21.92% epithelial lesions (16.44% epithelial tumors, and 5.48% dermoid cysts).
Conclusion: Lacrimal fossa lesions show a wide pathological range. Inflammatory lesions are most frequent, followed by lymphoproliferative and epithelial lesions. Analysis of clinical and radiological criteria is helpful in the differential diagnosis of lacrimal gland lesions.

Keywords: lacrimal gland, tumor, clinical and imaging criteria

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