Back to Journals » Clinical Ophthalmology » Volume 4

Ketamine versus propofol for strabismus surgery in children

Authors Mizrak A, Erbagci I, Arici T, Ozcan I, Ganidagli S, Tatar G, Oner U

Published 1 July 2010 Volume 2010:4 Pages 673—679


Review by Single anonymous peer review

Peer reviewer comments 2

Ayse Mizrak1, Ibrahim Erbagci2, Tulin Arici1, Ibrahim Ozcan1, Gurkan Tatar2, Unsal Oner1

1Anesthesiology and Reanimation, Gaziantep University School of Medicine, Gaziantep, Turkey; 2The Department of Ophthalmology, Gaziantep University School of Medicine, Gaziantep, Turkey

Purpose: To compare the effects of intravenous infusion of ketamine and propofol anesthesia in children undergoing strabismus surgery.
Methods: Sixty pediatric patients aged 4–11 years were enrolled for the study. Patients in Group K were infused ketamine 1–3 mg/kg/hr (n = 30) and patients in Group P were infused with propofol
6–9 mg/kg/hr (n = 30). After giving fentanyl 1 µg/kg and rocuronium bromide 0.5 mg/kg, patients were intubated.
Results: The consumption of anesthetics (P = 0.0001) and antiemetics (P = 0.004), the incidence of ­oculocardiac reflex (P = 0.02) in Group K were significantly lower than in Group P. The recovery time (P = 0.008), postoperative agitation score (P = 0.005), Face Pain Scale (P = 0.001), Ramsay Sedation Score (P = 0.01) during awakening and at postoperative 30th min (P = 0.02) in Group K were significantly lower than in Group P. The postoperative agitation score ­during awakening was significantly lower than the preoperative values in Group K (P = 0.0001).
Conclusions: The infusion of ketamine is more advantageous than the infusion of propofol in children for use in strabismus surgery.

Keywords: ketamine, propofol, pediatrics, strabismus, surgery

Creative Commons License © 2010 The Author(s). This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License. By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.