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Hepatic Medicine: Evidence and Research
Beth Israel Deaconess Medical Center, Harvard Medical School, United States
Editor-in-Chief: Dr Gerond Lake-Bakaar
Dr Lake-Bakaar has worked extensively in both clinical and laboratory research. He served as Medical Research Council lecturer to Dame Sheila Sherlock (1977-1982) and as Solomon A. Berson Fellow (1980-81) with Rosalyn Yalow (Nobel laureate in medicine and physiology 1977). He worked in the pharmaceutical industry from 1982 to 1985 as director of medical affairs to Janssen Pharmaceutica, a subsidiary of Johnson & Johnson, a Fortune 500 company with a renowned reputation for its training in business and management skills. In 1992, he founded the website http://www.findadoc.com/. He was chief of gastroenterology and head of the Hepato-Biliary program at VA Medical Center Northport, from January 1990 to March 2003, and concomitantly was director of the GI fellowship program at Health Sciences Center, State University of Stony Brook.
Dr Lake-Bakaar has had extensive experience in the practice of clinical gastroenterology, including advanced techniques such as endoscopic retrograde cholangio-pancreatography. More recently, from 2003 to 2007, he worked at the Center for the Study of Hepatitis C, which combined clinical research in the Division of GI-Hepatology at Weill Cornell Medical College with the highest quality of basic science research in HCV virology in the Charles M. Rice laboratory at Rockefeller University. This broad experience at the highest level in clinical medicine, basic science and applied science within the pharmaceutical industry has afforded him a unique perspective in academic medicine.
Among his original research was the first description of AIDS gastropathy, which established hypochlorhydria in patients with HIV infection and led to the demonstration that significant improvement in ketoconazole bioabsorption ensued when the drug was given with dilute hydrochloric acid.
His current research interests center on chronic hepatitis C liver disease and the role of B cells in controlling chronic hepatitis C viremia. He is also focused on the development of methods for harnessing secondary host immune response to control viremia in both chronic hepatitis B and B infections. He is currently hepatologist, transplant hepatologist and co-director of a liver tumor center at Beth Israel Deaconess Medical Center, Harvard Medical School in Boston.
Gianfranco D. Alpini, Distinguished Professor, Medical Physiology, Director of Baylor Scott & White DDRC, Central Texas Veterans Health Care Systems, Texas A & M University Health Science Center, Dr. Nicholas C. Hightower Centennial Chair in Gastroenterology Baylor Scott & White, Temple, TX, USA
Christopher D. Batich, Grodsky Professor, Departments of Biomedical Engineering and Materials Science and Engineering, University of Florida, Gainesville, FL, USA
Asim Dasgupta, Professor, Department of Microbiology and Immunology, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA
Ming Hu, Professor, Department of Pharmacological and Pharmaceutical Sciences, College of Pharmacy, University of Houston, Houston, TX, USA
Hartmut Jaeschke, Professor, Department of Pharmacology, Toxicology and Therapeutics, The University of Kansas Medical Center, Kansas City, Kansas, USA
Hyam L. Leffert, M.D., Professor of Pharmacology, Hepatocyte Growth Control and Stem Cell Laboratory, School of Medicine, UCSD Cancer Center, University of California, San Diego, California, USA
Joseph Locker, Professor, Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
Joseph L. Messina, Professor, Departments of Pathology, Cell, Developmental, & Integrative Biology, and Biochemistry & Molecular Genetics Division of Molecular and Cellular Pathology, The University of Alabama at Birmingham
Sonia M. Najjar, Associate Dean of Research and Innovation Professor, Department of Biomedical Sciences, Ohio University, Athens, OH, USA
Raymond F. Schinazi, Frances Winship Walters Professor of Pediatrics, Emory University School of Medicine, Director, Laboratory of Biochemical Pharmacology, Director, HIV Cure Scientific Working Group, Emory University Center for AIDS Research, Atlanta, GA, USA
Brett T. Spear, Professor, Departments of Microbiology, Immunology and Molecular Genetics, Pathology and Laboratory Medicine, University of Kentucky College of Medicine, Lexington, KY, USA
Clifford J. Steer, Professor of Medicine, Genetics, Cell Biology and Development, Director, Molecular Gastroenterology Program, University of Minnesota Medical School, Minneapolis, MN, USA
Liang Wang, Professor, Professor, Department of Radiology, Tongji Hospital, Tongji Medical College Huazhong University of Science & Technology, Wuhan, People's Republic of China
Martin L. Yarmush, MD, PhD, Paul and Mary Monroe Chair of Science and Engineering and Distinguished Professor of Biomedical Engineering, Rutgers University, Piscataway, NJ, USA