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Is portal vein thrombosis still a contraindication for liver transplantation? A single-institute’s 5-year experience and literature review

Authors Ghazwani S, Panaro F, Navarro F

Received 20 June 2016

Accepted for publication 22 August 2016

Published 18 November 2016 Volume 2016:8 Pages 31—36


Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 3

Editor who approved publication: Professor Qing Yi

S Ghazwani, F Panaro, F Navarro

Department of Transplant Unit, Saint Eloi University Hospital, University of Montpellier, Montpellier, France

Background/purpose: Portal vein thrombosis (PVT) is a common problem in candidates for liver transplantation (LT). PVT is a well-recognized complication of patients with end-stage liver disease and its incidence ranges from 2% to 26%. The total PVT still represents an absolute contraindication for an LT. Various techniques of PV revascularization have been proposed; however, the results are far from optimal.
Objective: The aim of this article is to report our experience in LT with PVT and to analyze the latest literature in this field.
Materials and methods: In the past 5 years, 317 LTs were performed in 317 patients. Twenty-one (6.6%) of them had a PVT (19 partial and two total).
Results: During transplantation, a total thrombectomy was performed in 13 cases and a partial thrombectomy in the remaining six patients. In case of total thrombectomy, a left renovascular revascularization was performed in one case and a left gastric vein revascularization in the other. No cases of PVT recurrence were reported in the early follow-up.
Conclusion: PVT no longer represent an absolute contraindication for an LT.

Keywords: reno-portal anastomosis, portal vein thrombosis, nonanatomical revascularization

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