Is portal vein thrombosis still a contraindication for liver transplantation? A single-institute’s 5-year experience and literature review
Authors Ghazwani S, Panaro F, Navarro F
Received 20 June 2016
Accepted for publication 22 August 2016
Published 18 November 2016 Volume 2016:8 Pages 31—36
Checked for plagiarism Yes
Review by Single-blind
Peer reviewers approved by Dr Amy Norman
Peer reviewer comments 3
Editor who approved publication: Professor Qing Yi
S Ghazwani, F Panaro, F Navarro
Department of Transplant Unit, Saint Eloi University Hospital, University of Montpellier, Montpellier, France
Background/purpose: Portal vein thrombosis (PVT) is a common problem in candidates for liver transplantation (LT). PVT is a well-recognized complication of patients with end-stage liver disease and its incidence ranges from 2% to 26%. The total PVT still represents an absolute contraindication for an LT. Various techniques of PV revascularization have been proposed; however, the results are far from optimal.
Objective: The aim of this article is to report our experience in LT with PVT and to analyze the latest literature in this field.
Materials and methods: In the past 5 years, 317 LTs were performed in 317 patients. Twenty-one (6.6%) of them had a PVT (19 partial and two total).
Results: During transplantation, a total thrombectomy was performed in 13 cases and a partial thrombectomy in the remaining six patients. In case of total thrombectomy, a left renovascular revascularization was performed in one case and a left gastric vein revascularization in the other. No cases of PVT recurrence were reported in the early follow-up.
Conclusion: PVT no longer represent an absolute contraindication for an LT.
Keywords: reno-portal anastomosis, portal vein thrombosis, nonanatomical revascularization
This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License. By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.Download Article [PDF] View Full Text [HTML][Machine readable]