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Iron Deficiency Anemia Refractory to Conventional Therapy but Responsive to Feralgine® in a Young Woman with Celiac Disease

Authors Talarico V, Giancotti L, Miniero R, Bertini M

Received 22 November 2020

Accepted for publication 14 January 2021

Published 16 February 2021 Volume 2021:14 Pages 89—93

DOI https://doi.org/10.2147/IMCRJ.S291599

Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 3

Editor who approved publication: Professor Ronald Prineas


Valentina Talarico,1 Laura Giancotti,2 Roberto Miniero,1 Marco Bertini3

1Department of Pediatric, Pugliese-Ciaccio Hospital, Catanzaro, Italy; 2Unit of Pediatrics, University “Magna Graecia”, Catanzaro, Italy; 3R&D Department, Laboratori Baldacci SpA, Pisa, Italy

Correspondence: Valentina Talarico
Department of Pediatrics, Pugliese-Ciaccio Hospital, Viale Pio X, Catanzaro, 88100, Italy
Tel +3402457848
Email talaricovalentina@gmail.com

Abstract: Iron, which is an important micronutrient in the human body may be deficient in people with celiac disease (CD). Iron deficiency anemia (IDA) may be the presenting feature of celiac disease, also in the absence of diarrhea or weight loss. The treatment of IDA in patient with CD is primarily a gluten-free-diet (GFD), but it is also very important oral iron supplementation until the iron stores have been restored. However, a frequent problem in CD is the poor tolerability and poor efficacy of oral iron preparations. A new product, consisting of the combination of Ferrous Bysglicinate Chelate and Sodium Alginate (Feralgine™), has been demonstrated to be more bioavailable and well tolerated in CD. We present a case report that showed a clear efficacy of this product in a form of IDA refractory to conventional therapy in a woman with CD and we demonstrated a clear increase of serum iron after administration of this new type of ferrous.

Keywords: celiac disease, iron deficiency anemia, ferrous bisglycinate chelate, sodium alginate, OIAT

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