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Inter-Eye Vault Differences of Implantable Collamer Lens Measured Using Anterior Segment Optical Coherence Tomography

Authors Cerpa Manito S, Sánchez Trancón A, Torrado Sierra O, Baptista AMG, Serra PM

Received 24 April 2020

Accepted for publication 12 August 2020

Published 29 October 2020 Volume 2020:14 Pages 3563—3573

DOI https://doi.org/10.2147/OPTH.S258817

Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 4

Editor who approved publication: Dr Scott Fraser


Santiago Cerpa Manito,1 Angel Sánchez Trancón,1 Oscar Torrado Sierra,1 António MG Baptista,2 Pedro Miguel Serra1,3

1Ophthalmology Clinic Vista Sánchez Trancón, Badajoz, Spain; 2Centre of Physics, University of Minho, Braga, Portugal; 3Optics and Optometry Department, Instituto Superior de Educação e Ciências, Lisbon, Portugal

Correspondence: Pedro Miguel Serra Email pedro.serra@vistasancheztrancon.com

Purpose: The distance between an implantable collamer lens (ICL) and the crystalline lens, namely vault, is a space regulated by the interaction of the ICL and the anatomical structures of the eye. This study analysed the differences in vault size between fellow eyes with similar anterior segment biometry.
Patients and Methods: A retrospective case series analysed 109 cases of patients bilaterally implanted with EVO-V4c. Patients were analysed pre- and postoperatively using anterior segment optical coherence tomography. The range of vault inter-eye differences was defined as the 95% confidence interval of the differences. Bivariate correlation was applied to seek for associations between vault inter-eye differences with biometric and lens parameters (angle-to-angle, anterior chamber depth, crystalline lens rise, central corneal thickness, central keratometry, ICL spherical equivalent, horizontal compression, postoperative pupil diameter and vault).
Results: Mean vault inter-eye differences were similar between fellow eyes (26.0 ± 122.5 μm). The 95% confidence interval range of the differences was ± 240.1 μm, nearly 50% of the cases presented vault inter-eye differences higher than 100 μm. The vault of the first operated eye explained 81% of the variance in the second eye vault. Vault inter-eye differences were positively correlated with the level of horizontal compression and with vault magnitude.
Conclusion: Vaults measured in fellow eyes may present considerable differences, which can reach 25% of the common vault range. This reflects some degree of baseline variability in the vault. Clinically, these differences assume special relevance in cases where low or high vaults are expected.

Keywords: implantable collamer lenses, vault, inter-eye differences, variability

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