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Infectious optic neuropathies: a clinical update

Authors Kahloun R, Abroug N, Ksiaa I, Mahmoud A, Zeghidi H, Zaouali S, Khairallah M

Received 10 April 2015

Accepted for publication 1 July 2015

Published 28 September 2015 Volume 2015:7 Pages 59—81

DOI https://doi.org/10.2147/EB.S69173

Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 3

Editor who approved publication: Professor Margaret Wong-Riley


Rim Kahloun, Nesrine Abroug, Imen Ksiaa, Anis Mahmoud, Hatem Zeghidi, Sonia Zaouali, Moncef Khairallah

Department of Ophthalmology, Fattouma Bourguiba University Hospital, Faculty of Medicine, University of Monastir, Monastir, Tunisia

Abstract: Different forms of optic neuropathy causing visual impairment of varying severity have been reported in association with a wide variety of infectious agents. Proper clinical diagnosis of any of these infectious conditions is based on epidemiological data, history, systemic symptoms and signs, and the pattern of ocular findings. Diagnosis is confirmed by serologic testing and polymerase chain reaction in selected cases. Treatment of infectious optic neuropathies involves the use of specific anti-infectious drugs and corticosteroids to suppress the associated inflammatory reaction. The visual prognosis is generally good, but persistent severe vision loss with optic atrophy can occur. This review presents optic neuropathies caused by specific viral, bacterial, parasitic, and fungal diseases.

Keywords: optic neuropathy, viruses, bacteria, parasites, fungi, vaccination

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