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Impact of type 2 diabetes mellitus on hospitalization costs in older patients with acute myocardial infarction

Authors Fu KL, Fan GQ, Han L, Wang XZ, Wang J, Wang YS, Zhong M, Zhang Y, Zhang W, Wang ZH

Received 27 December 2013

Accepted for publication 1 February 2014

Published 25 April 2014 Volume 2014:9 Pages 711—718

DOI https://doi.org/10.2147/CIA.S59802

Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 2

Kai-li Fu,1 Guan-qi Fan,1 Lu Han,1 Xiao-zhen Wang,2 Jia Wang,1 Yu-shu Wang,1 Ming Zhong,1 Yun Zhang,1 Wei Zhang,1 Zhi-hao Wang3

1Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education and Chinese Ministry of Public Health, and Department of Cardiology, Qilu Hospital of Shandong University, 2Shandong University of Traditional Chinese Medicine, 3Department of Geriatric Medicine, Qilu Hospital of Shandong University, Ji'nan, People's Republic of China

Background: The purpose of this study was to evaluate the impact of type 2 diabetes mellitus on hospitalization costs in older patients with acute myocardial infarction (MI).
Methods: Retrospective analysis of data from the case retrieval system of Qilu Hospital of Shandong University located in Jinan city of Shandong Province was done for patients with acute MI from January 1, 2011 to December 31, 2012.
Results: Stenting was an important factor affecting older patients' total hospitalization costs (β=0.685, P=0.000) and treatment costs during the follow-up period (duration of hospital stay only, β=0.508, P=0.000). Stenting was also a protective factor in the prevention of acute heart failure (HF) in older patients with acute MI during the follow-up period (odds ratio 0.189, 95% confidence interval 0.059–0.602, P=0.005). Implementation of percutaneous coronary intervention reduced the incidence of acute HF in older inpatients with acute MI (27.8% versus 4.3%, P=0.001) and without diabetes (18.2% versus 3.8%, P=0.001). Moreover, among the elderly, the incremental cost-effectiveness ratio estimate for implementing percutaneous coronary intervention in diabetic patients was higher than in nondiabetic patients.
Conclusion: Stenting was a protective factor for preventing acute HF in the elderly during the follow-up period. From the perspective of reducing the incidence of acute HF in inpatients, implementation of percutaneous coronary intervention after an acute MI is more cost-effective in older patients with diabetes mellitus than in those without it.

Keywords: diabetes, aging, myocardial infarction, hospitalization costs, vascular

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