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Gynecomastia – evaluation and current treatment options

Authors Murad MH, Johnson, Kermott

Published 28 March 2011 Volume 2011:7 Pages 145—148


Review by Single-blind

Peer reviewer comments 2

Ruth E Johnson, Cindy A Kermott, M Hassan Murad
Mayo Clinic, Division of Preventive, Occupational and Aerospace Medicine, Rochester, Minnesota, USA
Date of preparation: 11th January 2011
Conflict of Interest: None declared

Clinical question: What is the best management approach for gynecomastia?
Results: In most patients, surgical correction usually leads to immediate cosmetic and symptomatic improvement and is considered the best approach. In men who are being treated with antiandrogen therapies, pharmacological intervention with tamoxifen is the most effective approach, followed by radiotherapy.
Implementation: Pitfalls to avoid when treating gynecomastia
 - Failure to detect the very rare male breast cancer
 - Overly aggressive early intervention or evaluation
 - Appropriate medical intervention
 - When to refer to specialist treatment

Keywords: gynecomastia, testosterone, estrogen

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