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Giant cell arteritis: A rare cause of posterior vasculitis

Authors Moschos M, Guex-Crosier Y

Published 10 December 2008 Volume 2009:3 Pages 111—115


Review by Single-blind

Peer reviewer comments 6

Marilita M Moschos1, Yan Guex-Crosier2

1Department of Ophthalmology, University of Athens, Greece; 2Jules Gonin Eye Hospital, University of Lausanne, Switzerland

Purpose: To report three cases of posterior vasculitis associated with subacute giant cell arteritis (GCA).

Methods: Three patients with decreased vision underwent complete ophthalmologic examination and fluorescein angiography.

Results: All patients presented posterior vasculitis. Patient 1 had an erythrocyte sedimentation rate (ESR) of 38 mm/hr and a C-reactive protein (CRP) of 28mg/L. Patient 2 and 3 had an ESR of 104 and 95 mm/hr and a CRP of 42 and 195 mg/L accordingly. Diagnosis was established by temporal artery biopsy. Resolution was observed after systemic prednisolone therapy.

Conclusion: GCA should be suspected when posterior vasculitis and relatively high ESR and CRP are present.

Keywords: giant cell arteritis, posterior vasculitis Horton’s disease, temporal arteritis, uveitis

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