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Galectin-3: clinical utility and prognostic value in patients with heart failure

Authors Kramer F

Received 6 December 2012

Accepted for publication 3 January 2013

Published 7 February 2013 Volume 2013:4 Pages 13—22

DOI https://doi.org/10.2147/RRCC.S28562

Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 4


Frank Kramer

Clinical Sciences, Global Biomarker Strategy and Development, Bayer HealthCare, Wuppertal, Germany

Abstract: This review summarizes the key findings of 14 clinical trials in which Galectin-3 was assessed as a biomarker of heart failure. In addition, most relevant information available about Galectin-3 biology generated in in vitro and in vivo research is discussed in the context of heart failure.

Keywords: biomarker, cardiovascular disease, therapy monitoring, prediction of outcome, patient stratification

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