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Extensive superior limbic keratoconjunctivitis in Graves’ disease: case report and mini-review of the literature

Authors Chelala E, El Rami H, Dirani A, Fakhoury H, Fadlallah A

Received 19 December 2014

Accepted for publication 14 February 2015

Published 10 March 2015 Volume 2015:9 Pages 467—468

DOI https://doi.org/10.2147/OPTH.S79561

Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 5

Editor who approved publication: Dr Scott Fraser


Elias Chelala, Hala El Rami, Ali Dirani, Henry Fakhoury, Ali Fadlallah

Faculty of Medicine, Saint-Joseph University, Beirut, Lebanon

Background: Superior limbic keratoconjunctivitis (SLK) is characterized as an inflammation of the superior bulbar conjunctiva with predominant involvement of the superior limbus and adjacent epithelial keratitis.
Methods: A 51-year-old woman, with a history of medically controlled Graves’ disease was seen with an extensive SLK involving 5 mm of the superior cornea.
Results: Total remission was observed with topical steroids (DXM). Recurrence was observed 1 week after steroid discontinuation, and steroidal treatment was reintroduced with tapering over 1 month. Total remission was then observed for 1 year.
Conclusion: Extensive keratitis and vascular pannus in SLK is rarely reported. This form could be treated with topical steroids. Tapering treatment remains essential for long-term success.

Keywords: superior limbic keratoconjunctivitis, anti-inflammatory drugs, dexamethasone, triamcinolone, Graves’ disease

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