Evaluating vancomycin susceptibility in Staphylococcus aureus
Marcelo J Mimica, Alessandra Navarini
Department of Pathology, Division of Microbiology, Santa Casa de São Paulo School of Medicine, São Paulo, Brazil
We read the report by Phillips et al1 with great interest and would like to discuss it in comparison with our previous published data on the subject.2,3
We have also studied a number of Staphylococcus aureus clinical isolates (n=125), comparing different vancomycin susceptibility tests, including microdilution, Etest® (bio-Mérieux, Marcy-l’Étoile, France), and brain heart infusion vancomycin screening plates. We found only one isolate with reduced susceptibility with a minimum inhibitory concentration (MIC) =4 mg/L when tested with Etest and 2 mg/L when tested with microdilution.2,3 Our results showed a tendency of higher lethality when higher MICs were present, even within the susceptible range,3 as some previous studies have shown.4,5
View original paper by Phillips et al.
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