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Efficacy of deoxyspergualine for antibody-mediated rejection and proteinuria after kidney transplantation

Authors Hideki Ishida, Kazunari Tanabe

Published 6 June 2008 Volume 2008:4(3) Pages 641—644

DOI https://doi.org/10.2147/TCRM.S2499

Hideki Ishida, Kazunari Tanabe

Department of Urology, Tokyo Women’s Medical University, Tokyo, Japan

Abstract: A patient showing antibody-mediated rejection (AMR) with severe vasculitis, and massive proteinuria after kidney transplantation was treated with deoxyspergualine (DSG, Spanidin®, Nippon Kayaku). DSG showed marked efficacy for this patient’s symptoms. We report on a patient for whom DSG was effective against AMR after renal transplantation.

Keywords: deoxyspergualine (DSG), vascular rejection, antihuman leukocyte antigen (HLA) antibody

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