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Diffuse multibacillary leprosy patient with Lucio’s phenomenon and positive anticardiolipin antibody misdiagnosed as lupus erythematosus panniculitis in the People’s Republic of China

Authors Gao W, Chen Z, Jiang H, Shi Y, Zhang W, Wang H

Received 21 January 2019

Accepted for publication 21 February 2019

Published 2 April 2019 Volume 2019:12 Pages 741—744

DOI https://doi.org/10.2147/IDR.S202386

Checked for plagiarism Yes

Review by Single-blind

Peer reviewers approved by Dr Cristina Weinberg

Peer reviewer comments 2

Editor who approved publication: Dr Sahil Khanna


Wei Gao, Zhiming Chen, Haiqin Jiang, Ying Shi, Wenyue Zhang, Hongsheng Wang

Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Jiangsu Key Laboratory of Molecular Biology for Skin Diseases and STIs, Nanjing 210042, People’s Republic of China

Abstract: Lucio’s phenomenon (LP) is a special reactional state associated with diffuse multibacillary leprosy; both exhibit a limitative global distribution mainly in Mexico and Central America. We report a case of a 28-year-old female leprosy patient in the People’s Republic of China, together with LP and positive anticardiolipin antibody, characterized by vascular thrombosis and invasion of blood vessel walls by leprosy bacilli, causing extensive skin ulcers and followed by a large number of atrophic scars.

Keywords: Leprosy, Lucio’s phenomenon, anticardiolipin antibody

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