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Differential diagnosis and clinical management of diastolic heart failure: current best practice

Authors Tawil J, Gelzinis TA

Received 3 March 2016

Accepted for publication 18 June 2016

Published 29 September 2016 Volume 2016:7 Pages 117—135

DOI https://doi.org/10.2147/RRCC.S80291

Checked for plagiarism Yes

Review by Single-blind

Peer reviewers approved by Dr Lucy Goodman

Peer reviewer comments 2

Editor who approved publication: Dr Richard Kones

Justin Tawil,1 Theresa A Gelzinis2

1Department of Anesthesiology, Medical College of Wisconsin, Milwaukee, WI, 2Department of Anesthesiology, University of Pittsburgh, Pittsburgh, PA, USA


Abstract: As the population ages, the prevalence of diastolic dysfunction and heart failure with preserved ejection fraction is rising. The presentation and management of these patients is increasing in frequency and requires an understanding of its pathophysiology, diagnostic methodology, as well as modern therapy for optimal outcome. This review will discuss the mechanisms, clinical stages, diagnostic grading, and therapeutic options for the management of diastolic dysfunction.

Keywords: heart failure, echocardiography, diastolic dysfunction, preserved ejection fraction

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