Back to Journals » Clinical Ophthalmology » Volume 13

Diagnostic and Management Strategies of Aspergillus Endophthalmitis: Current Insights

Authors Spadea L, Giannico MI

Received 22 September 2019

Accepted for publication 16 December 2019

Published 24 December 2019 Volume 2019:13 Pages 2573—2582

DOI https://doi.org/10.2147/OPTH.S219264

Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 2

Editor who approved publication: Dr Scott Fraser


Leopoldo Spadea, Maria Ilaria Giannico

University “La Sapienza”, Department of Sense Organs, Eye Clinic, Rome, Italy

Correspondence: Leopoldo Spadea
Head Eye Clinic, Policlinico Umberto 1, “Sapienza” University of Rome, Via Benozzo Gozzoli 34, Rome 00142, Italy
Tel +39 06 519 3220
Fax +39 06 8865 7818
Email leopoldo.spadea@uniroma1.it

Abstract: Fungal endophthalmitis is subsequent to endogenous or exogenous infection and represents an important complication of ocular surgery which may lead to significant visual loss and blindness. The prognosis is poor because of delayed diagnosis and limited availability of effective antifungal drugs with good ocular penetration. Furthermore, the critical issue in diagnosing fungal infection of the eye is microbiological identification of the etiologic agent in clinical samples. Aspergillus is among the most frequent isolated organisms in fungal endophthalmitis. Early diagnosis is essential to prevent severe complications and blindness. Treatments include local, systemic and surgical therapeutic strategies. The purpose of the present review is the analysis of the current procedures adopted to promptly diagnose and treat Aspergillus endophthalmitis.

Keywords: Aspergillus, endophthalmitis, fungal infection, cataract surgery, ocular mycoses


Creative Commons License This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License. By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.

Download Article [PDF]  View Full Text [HTML][Machine readable]