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Cortical inputs to the middle temporal visual area in New World owl monkeys

Authors Cerkevich CM, Collins CE, Kaas JH

Received 26 June 2014

Accepted for publication 26 August 2014

Published 23 December 2014 Volume 2015:7 Pages 1—15

DOI https://doi.org/10.2147/EB.S69713

Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 5

Editor who approved publication: Professor Margaret Wong-Riley

Christina M Cerkevich,1 Christine E Collins,2 Jon H Kaas2

1Center for the Neural Basis of Cognition and Systems Neuroscience Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; 2Department of Psychology, Vanderbilt University, Nashville, TN, USA


Abstract: We made eight retrograde tracer injections into the middle temporal visual area (MT) of three New World owl monkeys (Aotus nancymaae). These injections were placed across the representation of the retina in MT to allow us to compare the locations of labeled cells in other areas in order to provide evidence for any retinotopic organization in those areas. Four regions projected to MT: 1) early visual areas, including V1, V2, V3, the dorsolateral visual area, and the dorsomedial visual area, provided topographically organized inputs to MT; 2) all areas in the MT complex (the middle temporal crescent, the middle superior temporal area, and the fundal areas of the superior temporal sulcus) projected to MT. Somewhat variably across injections, neurons were labeled in other parts of the temporal lobe; 3) regions in the location of the medial visual area, the posterior parietal cortex, and the lateral sulcus provided other inputs to MT; 4) finally, projections from the frontal eye field, frontal visual field, and prefrontal cortex were also labeled by our injections. These results further establish the sources of input to MT, and provide direct evidence within and across cases for retinotopic patterns of projections from early visual areas to MT.

Keywords: middle temporal area, visual cortex, parietal cortex

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