Correlation between body mass index and ocular parameters
Authors Panon N, Luangsawang K, Rugaber C, Tongchit T, Thongsepee N, Cheaha D, Kongjaidee P, Changtong A, Daradas A, Chotimol P
Received 30 November 2018
Accepted for publication 14 March 2019
Published 30 April 2019 Volume 2019:13 Pages 763—769
Checked for plagiarism Yes
Review by Single anonymous peer review
Peer reviewer comments 2
Editor who approved publication: Dr Scott Fraser
Nisa Panon,1 Kanin Luangsawang,2 Christopher Rugaber,1 Trinnawat Tongchit,1 Nattaya Thongsepee,3 Dania Cheaha,4 Pongnugoon Kongjaidee,5 Akawan Changtong,5 Adithep Daradas,5 Phatiwat Chotimol6
1Faculty of Optometry, Rangsit University, Pathumthani, Thailand; 2Department of Ophthalmology, Faculty of Medicine, Naresuan University, Phitsanulok, Thailand; 3Department of Preclinical Sciences (Physiology), Faculty of Medicine, Thammasat University, Pathumthani, Thailand; 4Department of Biology, Faculty of Science, Prince of Songkla University, Hat Yai, Thailand; 5Department of Optometry, Faculty of Allied Health Sciences, Naresuan University, Phitsanulok, Thailand; 6Department of Cardio-Thoracic Technology, Faculty of Allied Health Sciences, Naresuan University, Phitsanulok, Thailand
Purpose: To investigate the relationship between BMI and selected ocular parameters.
Subjects and methods: Fifty-three left eyes of normal weight subjects and 67 age-sex matched overweight subjects were studied. Inclusion criteria for the normal weight and overweight groups included BMI between 18.5–22.9 and 23.0–29.9 kg/m,2 respectively. Subjects with a history of systemic disease, ocular disease or surgery, or disability were excluded. All subjects underwent a medical history interview, arterial blood pressure, height, weight, waist circumference and hip circumference measurements, and BMI and waist-hip ratio calculation. The intraocular pressure (IOP) and anterior corneal curvature were measured by non-contact tonometry and corneal topography, respectively. Measurement of anterior and posterior segment parameters of the eye, including central corneal thickness, anterior chamber depth (ACD), anterior chamber angle, macular thickness (MT), ganglion cell thickness (GCT), retinal nerve fiber layer thickness, cup to disc ratio, and choroidal thickness was performed by enhanced depth-imaging optical coherence tomography.
Results: There was a positive correlation between ACD and BMI (Univariate analysis; β =0.198, P=0.030, Multivariate analysis; β =0.410, P=0.005) and between BMI and IOP (Univariate analysis; β =0.269, P=0.003). The IOP of the overweight group was found to be significantly higher than of the normal weight group (12.80±3.40 and 11.86±2.12 mm Hg, respectively, P=0.002). Also, there was a significant difference found between the GCT and the MT of the two groups (P=0.036 and 0.009, respectively).
Conclusion: It was found that BMI strongly correlated with ACD and IOP. Also, the degree of obesity was found to be a significant factor; therefore, the relationship between these ocular parameters and the severity of obesity should be further investigated.
Keywords: BMI, overweight, intraocular pressure, anterior chamber depth
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