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Correction of tear trough deformity with a cohesive polydensified matrix hyaluronic acid: a case series
Authors Huber-Vorländer J, Kürten M
Received 6 March 2015
Accepted for publication 1 May 2015
Published 25 June 2015 Volume 2015:8 Pages 307—312
DOI https://doi.org/10.2147/CCID.S84117
Checked for plagiarism Yes
Review by Single anonymous peer review
Peer reviewer comments 3
Editor who approved publication: Dr Jeffrey Weinberg

Jürgen Huber-Vorländer, Martin Kürten
Fort Malakoff Klinik, Mainz, Germany
Abstract: The tear trough or infraorbital hollow is a challenging area to treat, and only a few fillers are suitable for this delicate area. We report on a European case series of six subjects with mild to severe tear troughs who received treatment with cohesive polydensified matrix (CPM®) technology hyaluronic acid gel (Belotero® Balance). The product was injected as small depots (up to ten small boli 0.2 mL maximum each per side) at the supraperiosteal level along or below the orbital rim. Follow-up visits took place at 1, 3, 6, and 9 months after injection for independent evaluation of the clinical effect using the Merz Aesthetics Scale™ for infraorbital hollows and the Global Aesthetic Improvement Scale. Adverse events were also recorded. Mean hollowness scores were considerably improved compared with baseline in all subjects. In all women, the improvements remained throughout the 9-month study, with none reverting to their baseline score. Subjects’ satisfaction with treatment was very high throughout the study, and all women stated that they would repeat treatment with the same product. The CPM hyaluronic acid gel was well tolerated. CPM hyaluronic acid gel is a safe and effective treatment for the tear trough area.
Keywords: Belotero® Balance, cohesive polydensified matrix (CPM®), hyaluronic acid, infraorbital hollow, tear trough
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