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Corneal Hysteresis as a Biomarker of Glaucoma: Current Insights

Authors Zimprich L, Diedrich J, Bleeker A, Schweitzer JA

Received 13 May 2020

Accepted for publication 21 July 2020

Published 10 August 2020 Volume 2020:14 Pages 2255—2264

DOI https://doi.org/10.2147/OPTH.S236114

Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 2

Editor who approved publication: Dr Scott Fraser


Larae Zimprich,1 Jacob Diedrich,2 Adam Bleeker,3 Justin A Schweitzer1

1Vance Thompson Vision, Sioux Falls, SD 57108, USA; 2Mijangos Optometry, Sioux City, IA 51106, USA; 3University of South Dakota Sanford School of Medicine, Vermillion, SD 57069, USA

Correspondence: Justin A Schweitzer
Vance Thompson Vision, 3101 W 57th Street, Sioux Falls, SD 57108, USA
Tel +1605-361-3937
Fax +1605-371-7035
Email justin.schweitzer@vancethompsonvision.com

Abstract: The diagnosis and management of glaucoma has long been dependent on making decisions based on family history, optic nerve head evaluation, intraocular pressure, visual field testing, and optical coherence testing. Other pieces to aid in understanding glaucoma have presented throughout the years, including the role of corneal thickness. The discussion and debate on the mechanism of glaucoma have been attributed to resistance at the level of the conventional outflow pathway, perfusion pressure to the optic nerve head, cerebral spinal fluid pressure, and many more. Another piece that has emerged is corneal hysteresis, an assessment of the cornea’s ability to absorb and dissipate energy. There is abundant published literature supporting corneal hysteresis being associated with the presence and severity of glaucoma, the structural and functional progression of glaucoma, and the conversion to glaucoma. The supported data in these studies add another piece, corneal hysteresis, to consider in the diagnosis and management of glaucoma.

Keywords: glaucoma, corneal hysteresis, corneal biomechanics

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