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Complete response of a metastatic gastroesophageal adenocarcinoma on irinotecan-based chemotherapy in a dialysis patient

Authors J Verwimp, F Geurs, S Ponette, et al

Published 17 May 2010 Volume 2010:3 Pages 61—64

DOI http://dx.doi.org/10.2147/IJNRD.S7650

Review by Single-blind

Peer reviewer comments 2

J Verwimp1, F Geurs1, S Ponette2, J Ponette2, J Martens3, K Bulté2

1Department of Medical Oncology, 2Department of Gastroenterology, 3Department of Nephrology, Regionaal Ziekenhuis Sint-Maria, Ziekenhuislaan, Halle, Belgium

Abstract: We present the first case report of a complete response of metastatic gastroesophageal cancer in a chronic hemodialysis patient with irinotecan-based chemotherapy. An elderly dialysis patient presented with diffuse liver metastases by a gastroesophageal adenocarcinoma. He received combination chemotherapy with 5 fluorouracil and irinotecan. After six months of chemotherapy, liver scans show complete remission. The principles, practice, and experience of chemotherapy with irinotecan during dialysis are discussed.
Keywords: gastroesophageal cancer, irinotecan, chemotherapy, dialysis

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