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Comparison of a micro-electro-mechanical system airflow sensor with the pneumotach in the forced oscillation technique

Authors Xu XK, Harvey BP, Lutchen KR, Gelbman BD, Monfre SL, Coifman RE, Forbes CE

Received 24 July 2018

Accepted for publication 9 October 2018

Published 13 December 2018 Volume 2018:11 Pages 419—426

DOI https://doi.org/10.2147/MDER.S181258

Checked for plagiarism Yes

Review by Single-blind

Peer reviewers approved by Dr Justinn Cochran

Peer reviewer comments 2

Editor who approved publication: Dr Scott Fraser


Xiaohe K Xu,1 Brian P Harvey,2 Kenneth R Lutchen,2 Brian D Gelbman,3 Stephen L Monfre,1 Robert E Coifman,1 Charles E Forbes1

1Feather Sensors, LLC, Millville, NJ 08332, USA; 2Department of Biomedical Engineering, Boston University, Boston, MA 02215, USA; 3Division of Pulmonary and Critical Care Medicine, Weill Cornell Medical Center, New York, NY 10065, USA

Purpose: This study supports the use of thin-film micro-electro-mechanical system (MEMS) airflow sensors in the forced oscillation technique.
Materials and methods: The study employed static testing using air flow standards and computer-controlled sound attenuations at 8 Hz. Human feasibility studies were conducted with a testing apparatus consisting of a pneumotach and thin-film MEMS air flow sensors in series. Short-time Fourier transform spectra were obtained using SIGVIEW software.
Results: Three tests were performed, and excellent correlations were observed between the probes. The thin-film MEMS probe showed superior sensitivity to higher frequencies up to 200 Hz.
Conclusion: The results suggest that lower-cost thin-film MEMS can be used for forced oscillation technique applications (including home care devices) that will benefit patients suffering from pulmonary diseases such as asthma, COPD, and cystic fibrosis.

Keywords: pulmonary disease, pulmonary impedance, airway resistance, short-time Fourier transform, glottis closure

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