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Comparative Study of Two Short-Form Versions of the Montreal Cognitive Assessment for Screening of Post-Stroke Cognitive Impairment in a Chinese Population

Authors Wei J, Jin X, Chen B, Liu X, Zheng H, Guo R, Liang X, Fu C, Zhang Y

Received 9 February 2020

Accepted for publication 27 March 2020

Published 18 June 2020 Volume 2020:15 Pages 907—914

DOI https://doi.org/10.2147/CIA.S248856

Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 3

Editor who approved publication: Dr Zhi-Ying Wu


Jingjing Wei,1– 3,* Xianglan Jin,2,* Baoxin Chen,2 Xuemei Liu,4 Hong Zheng,4 Rongjuan Guo,2 Xiao Liang,3 Chen Fu,2,4 Yunling Zhang2,3

1Beijing University of Chinese Medicine, Beijing, People’s Republic of China; 2Department of Neurology, Dongfang Hospital, Beijing University of Chinese Medicine, Beijing, People’s Republic of China; 3Department of Neurology, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, People’s Republic of China; 4Central Laboratory, Dongfang Hospital, Beijing University of Chinese Medicine, Beijing, People’s Republic of China

*These authors contributed equally to this work

Correspondence: Yunling Zhang
Department of Neurology, Xiyuan Hospital, China Academy of Chinese Medical Sciences, 1 Xiyuan Playground, Haidian District, Beijing 100091, People’s Republic of China
Tel/Fax +86-10-6283-5960
Email yunlingzhang2004@126.com
Chen Fu
Central Laboratory, Dongfang Hospital, Beijing University of Chinese Medicine, 6 First Block, Fangxingyuan, Fengtai District, Beijing 100078, People’s Republic of China
Tel +86-10-6768-9634
Fax +86-10-67691949
Email fuchen2003@163.com

Purpose: Cognitive impairment (CI) is one of the most significant post-stroke complications. The Montreal Cognitive Assessment (MoCA) is widely applied to the early screening of post-stroke CI (PSCI), and has good sensitivity and specificity, but needs a long time to administer. Clinicians and researchers need shorter, more effective cognitive testing tools. The purpose of this study was to detect the sensitivity and specificity of two different short-form versions of the MoCA (SF-MoCA) for screening of PSCI in a Chinese population.
Methods: A total of 2,989 stroke participants were included from 14 hospitals in northern and southern China between June 2011 and September 2013. The sensitivity and specificity of the two SF-MoCA versions were compared.
Results: Using an MoCA score < 26 as the critical value, the National Institute of Neurological Disease and Stroke–Canadian Stroke Network SF-MoCA showed sensitivity of 91% and specificity of 63% (PPV 71%, BPV 87%) with scores ≤ 10 points. The sensitivity and specificity of the Bocti SF-MoCA were 92% and 69% (PPV 75%, BPV 89%) with scores ≤ 7, respectively. The area under the curve was 0.885 (95% CI 0.873– 0.897) and 0.912 (95% CI 0.902– 0.922), respectively.
Conclusion: The Bocti SF-MoCA can be used as a briefer and more effective screening tool for PSCI in Chinese.

Keywords: cognitive dysfunction, Montreal Cognitive Assessment, MoCA, stroke, sensitivity, specificity

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